TERPENE
Caryophyllene
Spicy, peppery, woody
The only terpene that directly binds CB2 receptors.
Effects & Benefits
Found In Nature
Caryophyllene is a naturally occurring compound found in many plants beyond cannabis:
Aroma Profile
Common THCA Strains
These strains are frequently associated with high Caryophyllene concentrations:
Entourage Effect
⬡Uniquely binds CB2 receptors directly — the only terpene classified as a dietary cannabinoid
The entourage effect refers to the synergistic interaction between cannabinoids, terpenes, and other phytochemicals in the cannabis plant. Whole-plant extracts and full-spectrum products preserve this synergy; isolated distillates do not.
Vaporization Temperature
Caryophyllene vaporizes at 130°C (266°F). To preserve this terpene when vaping, keep your device below this temperature — most terpenes degrade and produce harsh byproducts when overheated.
Shop Caryophyllene-rich products
Browse THCA products with caryophyllene in their terpene profile.