Sesquiterpene
Caryophyllene
Spicy, peppery, woody
The only terpene that directly binds CB2 receptors.
- Formula
- C₁₅H₂₄
- Boiling point
- 130°C
Effects & Benefits
Aroma Profile
Found In Nature
Caryophyllene is a naturally occurring compound found in many plants beyond cannabis:
Common THCA Strains
These strains are frequently associated with high Caryophyllene concentrations:
Entourage Effect
◈Uniquely binds CB2 receptors directly — the only terpene classified as a dietary cannabinoid
The entourage effect refers to the synergistic interaction between cannabinoids, terpenes, and other phytochemicals in the cannabis plant. Whole-plant extracts and full-spectrum products preserve this synergy; isolated distillates do not.
Vaporization Temperature
Caryophyllene vaporizes at 130°C (266°F). To preserve this terpene when vaping, keep your device below this temperature.
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